Clinically proven to help Increase Telomerase, reduce wrinkles, improve skin firmness, and elasticity.

Rejuvenate Serum

Telomerase Activating Skincare, A light, cooling gel with a velvety feel.  Non-tacky and non-greasy it absorbs almost instantly into the skin.


•Reduces Wrinkles and Blemishes
•Repairs Telomeres 
•More Luminous, Youthful Skin

The face of anti-aging has changed forever. Siorai Serum contains an active ingredient called TAM-818, the strongest of nearly 300,000 compounds tested over 11 years by award-winning Telomere Biologist Dr. Bill Andrews and his team at Sierra Sciences.

Clinical trials at Abich Labs in Italy show that after 30 days One Truth 818 decreased wrinkles by 14.04%, improved skin firmness by 20.33% and elasticity by 8.33%.

I am not the normal guy who writes reviews for anything. But this Siorai product has been my secret weapon against Father Time. I started using the product about a year ago and I have seen so much improvement. At 60+ years of age, no one told me when I was young to protect my skin, and I did not, the tanner the better. So I started the Siorai with sun damage and uneven skin. Now 12 months later used with my normal skin products, my skin is so much better. When I look in the mirror I don’t think I am looking at my Father. Give Siorai a try, you won’t be sorry!


San Diego, CA

Telomere Science

At the tips of every chromosome in the human body is a biological “clock” called the “telomere”. When a cell divides, its telomeres get shorter as a normal part of cell division. As a cell’s telomeres get shorter, it functions less effectively. Eventually, the telomere becomes critically short, cell division stops and the cell eventually atrophies and dies. Telomere shortening is a primary cause of many age-related diseases, including heart disease, arthritis, and COPD, while telomere shortening in the cells of our immune system progressively limits the body’s ability to fight infectious diseases, as well as cancer.

The enzyme telomerase has been shown to re-lengthen telomeres. Telomerase cannot be added to cells directly, but there is a gene for producing telomerase in every cell of the body. This gene is active in reproductive cells, but in most cells it is turned off.  Siorai serum can turn it back on.

The 2009 Nobel Prize for Medicine was awarded to the scientists who, in the mid 1980s, did research that later led to understanding the role of telomeres and telomerase. Since the awarding of this Nobel Prize, public interest in telomerase-based anti-aging therapies has soared. Further fueling the excitement over telomerase research was a January 2011 article in the journal Nature describing a study demonstrating that activating telomerase in mice actually reversed their aging—the clearest proof of concept yet that aging can be reversed through telomerase induction.

How does Telomerase Activation work?

When it comes to Telomerase Activation, no other company can offer you as effective a product as Siorai can. The science of telomeres has been around for decades. In fact, their discovery heralding a Nobel Prize back in 2009 and the discovery of the Hayflick limit (discovering that cells have a pre-destined, finite lifespan) happening 4 decades ago. In the scientific community, these discoveries are not new, but the technology is. And now that we have legit and scientifically sound methods of reversing age by lengthening the telomere mainstream media is carrying the message to the non-scientific community. People all over are beginning to ask, ‘how can I lengthen my telomeres?’ and ‘where can I buy something that will reverse my cellular aging?’ Soon, you will be able to answer, ‘from us.’

The End Replication Problem

When a cell divides, the genetic material inside that cell needs to be copied. This process is called DNA replication. The limitation on
Cell division is rooted in the very nature of DNA replication. The enzymes that replicate a strand of DNA are unable to continue replicating all the way to the end, which causes the loss of some DNA.

This is one of the reasons the telomere is essential. Repetitive sequences of DNA give us a “buffer” of genetic material that contains no (essential) information, so it can be safely consumed as part of the normal DNA replication process. Most of the cells in our bodies are in a constant state of division. Every system in our body suffers damage and needs regular upkeep, and cell division is the body’s primary method of performing that upkeep. Many of our cells divide yearly to keep our organs functioning. And with every division, the telomere shortens a little more, and a little more, until it becomes so short that any further division would start eating into our genetic information and mutations that can lead to cell death.

Telomeres, like all DNA, are made up of units called nucleotides, arranged like beads on a string. In the human genetic code, all our genetic information is coded using four nucleotides: adenine, guanine, cytosine, and thymine. The nucleotides in human telomeres are arranged in the repeating sequence TTAGGG (two thymine nucleotides, one adenine nucleotide, and three guanine nucleotides). This sequence is repeated thousands of times in tandem in every telomere. When we are first conceived, the telomeres in our single-cell embryos are approximately 15,000 nucleotides long. Our cells divide rapidly in the womb. By the time we are born, our telomeres have decreased in length to approximately 10,000 nucleotides. They shorten throughout our lifetime. When they reach an average of about 5,000 nucleotides, our cells cannot divide any further (the Hayflick Limit), and we die of old age.

So how does Telomerase Activating Skincare Work?

As mentioned before Siorai Serum is one of the world’s strongest telomerase inducers ever created. 100 Volunteers showed visible improvements to their wrinkles, pigmentation and tone of their skin.  All volunteers showed reversals of major signs of aging in as little as 2 weeks (measured clinically).

Our clinical, medically run tests were performed at Abich Laboratories in Italy and carried out on 100 volunteers, women aged between 35-65 years old, over a one month period with measurements and results taken half way at day 15.

This testing is over and above any ‘recommended’ number of volunteers in order to prove, without a doubt, the efficacy of topical telomerase activation.

Full Ingredients lists

Water, Jojoba Esters, Macadamia integrifolia Seed Oil, Ethyl Macadamiate, Isoamyl Laurate, Sodium Acrylates Copolymer, Glycerin, Tam-818, Helianthus Annuus (Sunflower) Seed Oil,Caprylhydroxamic Acid, Glyceryl Caprylate , Hydrogenated Polyisobutene, Lecithin, Phospholipids, Polyglyceryl-6 Caprylate, Polyglyceryl-10 Stearate, Propanediol, Tocopherol, Isopropyl Myristate, Citric Acid, Potassium Sorbate, Sodium Phytate, Fragrance (EcoCertified), Limonene, Linalool.


Rich in phospholipids such as sunflower and lecithin, omega 3 and 6 fatty acids, jojoba esters and macadamia emollients make Siorai Serum incredibly hydrating to the skin. As well as phenomenal visual age reversal of the skin, tests also show a decrease in trans-epidermal water loss, an increase in elastin production and a decrease in pigmentation and enlarged pores. 

The Hero product of the range will soon build a cult following, this serum is like no other.  Perfect for all skin types with the exception of very oily or acneic skins due to it’s high performing oil content.

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